PRI-MUS™ (prostate risk identification using
micro-ultrasound) is an evidence-based*
protocol for identifying sonographic features of
the prostate under micro-ultrasound to help
direct and target biopsies.
Small regular ducts
TARGET SUSPICIOUS REGION
or Bright Echoes in
or mottled” or Bright
Echoes (”Starry Sky”)
lesions or Irregular
CLICK on any image to enlarge
PRI-MUS 1 & 2
For PRI-MUS 1 and 2 features —
which are characteristically
benign, the urologist would take
a systematic biopsy.
PRI-MUS 3 characteristics could
be supported by targeted or
systematic biopsy, depending on
the suspiciousness of the tissue.
PRI-MUS 4 & 5
For PRI-MUS 4 and 5 features, the
urologist would target those
areas which are highly
correlated to significant disease.
*The initial PRI-MUS protocol was validated with data from 400 micro-ultrasound biopsy-based
cineloops matched to pathological results.
** The accompanying study has been published in the Journal of Urology: Ghai, S. et al., “Assessing
Cancer Risk in Novel 29 MHz Micro-Ultrasound Images of the Prostate: Creation of the Protocol of
Prostate Risk Identification Using Micro-Ultrasound”, Journal of Urology, Paper In Press: June 2016,